Garmaine Staff asked 2 years ago

According to the sign shown in this post on Reddit, using methamphetamine and dental anesthetic together is lethal.

Sign supposedly at a dentist's, transcribed below

If you use Methamphetamines (Crystal Meth, Crank, Speed, Glass, Tweak, Yaba)
Within 12 hours of a dental appointment. You need to tell us because dental anesthetic will Kill You.

  1. Is this true?
  2. What's the mechanism?
  3. What about methylphenidate, which is used as a treatment for ADHD and is often likened to methamphetamine by laypeople?